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OTUB2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73475Amount:
100ulMolecular Weight:
： 27213DaPurification:
： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
： The antiserum was produced against synthesized peptide derived from human OTUB2. AA range:133-182Source:
： Polyclonal, Rabbit
- Western Blot analysis of various cells using OTUB2 Polyclonal Antibody diluted at 1:2000
Gene Name:
： OTUB2Dilution:
： Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
： Ubiquitin thioesterase OTUB2Human Gene Id:
： 78990Human Swiss Prot No:
： Q96DC9Mouse Swiss Prot No:
： Q9CQX0Specificity:
： OTUB2 Polyclonal Antibody detects endogenous levels of OTUB2 protein.Formulation:
： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
： 1 mg/mlStorage Stability:
： -20°C/1 yearOther Name:
： OTUB2; C14orf137; OTB2; OTU2; Ubiquitin thioesterase OTUB2; Deubiquitinating enzyme OTUB2; OTU domain-containing ubiquitin aldehyde-binding protein 2; Otubain-2; Ubiquitin-specific-processing protease OTUB2Observed Band(KD):
： 27Background:
： OTU deubiquitinase, ubiquitin aldehyde binding 2(OTUB2) Homo sapiens This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011],Function:
： function:Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,similarity:Belongs to the peptidase C65 family.,similarity:Contains 1 OTU domain.,tissue specificity:Widely expressed. Expressed at higher level in brain.,Subcellular Location:
： nucleus,Expression:
： Widely expressed. Expressed at higher level in brain.
- Western blot analysis of lysates from COLO, HepG2, Jurkat, 293, and HT-29 cells, using OTUB2 Antibody. The lane on the right is blocked with the synthesized peptide.
Mouse Gene Id:
： 68149
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