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Oct-1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73230Amount:
100ulMolecular Weight:
76472DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human POU2F1/OCT1. AA range:361-410Source:
Polyclonal, Rabbit
- Western blot analysis of lysates from HepG2 cells, using POU2F1/OCT1 Antibody. The lane on the right is blocked with the synthesized peptide.
Gene Name:
POU2F1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
POU domain class 2 transcription factorHuman Gene Id:
5451/5452Human Swiss Prot No:
P14859/P09086Mouse Gene Id:
18986/18987Rat Gene Id:
171068Rat Swiss Prot No:
P31503Specificity:
Oct-1 Polyclonal Antibody detects endogenous levels of 40817 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
POU2F1; OCT1; OTF1; POU domain; class 2, transcription factor 1; NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1; POU2F2; OCT2; OTF2; POU domain, class 2, transcription factor 2; Lymphoid-restricted imObserved Band(KD):
100Background:
POU class 2 homeobox 1(POU2F1) Homo sapiens The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010],Function:
function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.,PTM:Phosphorylated by PRKDC.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR, PGR and HCFC1.,tissue specificity:Ubiquitous. Isoform 2 is lymphocyte-specific.,Subcellular Location:
Nucleus.Expression:
Ubiquitous. Isoform 2 is lymphocyte-specific.
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