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Cell Signal Transduction Research Antibodies
OATP-C Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight76449 Da
Protein NameSolute carrier organic anion transporter family member 1B1
Human Gene Id10599
Human Swiss Prot NoQ9Y6L6
SpecificityOATP-C Polyclonal Antibody detects endogenous levels of OATP-C protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6; Solute carrier organic anion transporter family member 1B1; Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solut
Observed Band(KD)76
Functionfunction:Mediates the Na(+)-independent transport of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. May play an important role in the clearance of bile acids and organic anions from the liver.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,subcellular location:Detected in basolateral membranes of hepatocytes.,tissue specificity:Highly expressed in liver. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.,
Subcellular Locationplasma membrane,integral component of plasma membrane,membrane,integral component of membrane,basolateral plasma membrane,
ExpressionLiver,PCR rescued clones,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human SLCO1B1. AA range:251-300
Gene NameSLCO1B1
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundsolute carrier organic anion transporter family member 1B1(SLCO1B1) Homo sapiens This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-73222-Conjugate. Price: $485 / Size: 100μl.
E20-73222-FITC$485 / 100μlE20-73222-Biotin$485 / 100μlE20-73222-HRP$485 / 100μlE20-73222-AP$485 / 100μlE20-73222-AF350$485 / 100μlE20-73222-AF405M$485 / 100μlE20-73222-AF488$485 / 100μlE20-73222-AF514$485 / 100μlE20-73222-AF532$485 / 100μlE20-73222-AF555$485 / 100μlE20-73222-AF568$485 / 100μlE20-73222-AF405S$485 / 100μlE20-73222-AF405L$485 / 100μlE20-73222-AF546$485 / 100μlE20-73222-AF594$485 / 100μlE20-73222-AF610$485 / 100μlE20-73222-AF635$485 / 100μlE20-73222-AF647$485 / 100μlE20-73222-AF680$485 / 100μlE20-73222-AF700$485 / 100μlE20-73222-AF750$485 / 100μlE20-73222-AF790$485 / 100μlE20-73222-APC$485 / 100μlE20-73222-PE$485 / 100μlE20-73222-Cy3$485 / 100μlE20-73222-Cy5$485 / 100μlE20-73222-Cy5.5$485 / 100μlE20-73222-Cy7$485 / 100μlE20-73222-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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