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Nur77 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-73213

  • Amount:

    100ul

  • Molecular Weight:

    64463Da

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human Nuclear Receptor NR4A1. AA range:317-366

  • Source:

    Polyclonal, Rabbit

  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Nuclear Receptor NR4A1 Antibody. The picture on the right is blocked with the synthesized peptide.

  • Gene Name:

    NR4A1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Nuclear receptor subfamily 4 group A member 1

  • Human Gene Id:

    3164

  • Human Swiss Prot No:

    P22736

  • Mouse Gene Id:

    15370

  • Mouse Swiss Prot No:

    P12813

  • Rat Gene Id:

    79240

  • Rat Swiss Prot No:

    P22829

  • Specificity:

    Nur77 Polyclonal Antibody detects endogenous levels of Nur77 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3

  • Observed Band(KD):

    60

  • Background:

    nuclear receptor subfamily 4 group A member 1(NR4A1) Homo sapiens This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],

  • Function:

    function:Orphan nuclear receptor.,induction:By growth-stimulating agents.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR4 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with GADD45GIP1.,tissue specificity:Fetal muscle and adult liver, brain and thyroid.,

  • Subcellular Location:

    Nucleus . Cytoplasm . Mitochondrion . Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). .

  • Expression:

    Fetal muscle and adult liver, brain and thyroid.

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Catalog Number

  • Amount:100ul
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Nur77 Polyclonal Antibody | EnoGene Biotech Co. Ltd