Product Information
Molecular Weight18697Da
Protein NameProstaglandin E synthase 3
Human Gene Id10728
Human Swiss Prot NoQ15185
Mouse Gene Id1.00044e+008
Mouse Swiss Prot NoQ9R0Q7
Rat Gene Id362809
Rat Swiss Prot NoP83868
SpecificityPhospho-p23 (S113) Polyclonal Antibody detects endogenous levels of p23 protein only when phosphorylated at S113.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePTGES3; P23; TEBP; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23
Observed Band(KD)24
Functioncatalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate.,function:Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the p23/wos2 family.,similarity:Contains 1 CS domain.,subunit:Binds to telomerase and to the progesterone receptor.,
Subcellular Locationchromosome, telomeric region,nucleus,nucleoplasm,telomerase holoenzyme complex,cytoplasm,cytosol,extracellular exosome,
ExpressionEmbryonic kidney,Epithelium,Liver,Lung,Pituitary,Platelet,T-cell,Testis,Uri