Product Information
Molecular Weight(Da):14478
Protein NameNuclear transport factor 2
Human Gene Id10204
Human Swiss Prot NoP61970
Mouse Gene Id621832
Mouse Swiss Prot NoP61971
Rat Gene Id291981
Rat Swiss Prot NoP61972
SpecificityNTF2 Polyclonal Antibody detects endogenous levels of NTF2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNUTF2; NTF2; Nuclear transport factor 2; NTF-2; Placental protein 15; PP15
Observed Band(KD)15
Functionfunction:Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.,similarity:Contains 1 NTF2 domain.,subunit:Homodimer.,
Subcellular LocationCytoplasm, cytosol . Nucleus outer membrane . Nucleus, nuclear pore complex . Nucleus inner membrane . Nucleus, nucleoplasm . At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci. .
ExpressionLung,
BackgroundThis gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016],