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NT-4 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73197Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human NT-4. AA range:71-120Source:
Polyclonal, RabbitGene Name:
NTF4Dilution:
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
- Immunohistochemical analysis of paraffin-embedded Human prostate cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Background:
neurotrophin 4(NTF4) Homo sapiens This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008],Protein Name:
Neurotrophin-4Human Gene Id:
4909Human Swiss Prot No:
P34130Mouse Gene Id:
78405Mouse Swiss Prot No:
Q80VU4Rat Gene Id:
25730Rat Swiss Prot No:
P34131Specificity:
NT-4 Polyclonal Antibody detects endogenous levels of NT-4 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
NTF4; NTF5; Neurotrophin-4; NT-4; Neurotrophin-5; NT-5; Neutrophic factor 4MolecularWeight(Da):
22427Function:
function:Target-derived survival factor for peripheral sensory sympathetic neurons.,similarity:Belongs to the NGF-beta family.,tissue specificity:Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.,Subcellular Location:
extracellular region,endoplasmic reticulum lumen,cytoplasmic, membrane-bounded vesicle,Expression:
Ovary,Prostate,
- Immunohistochemistry analysis of NT-4 antibody in paraffin-embedded human prostate carcinoma tissue.
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