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NPY5-R Polyclonal Antibody
Datasheet
Catalog Number:
E20-73185Amount:
100ulMolecular Weight:
51991DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human NPY5R. AA range:221-270Source:
Polyclonal, Rabbit
- Western Blot analysis of various cells using NPY5-R Polyclonal Antibody
Gene Name:
NPY5RDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Neuropeptide Y receptor type 5Human Gene Id:
4889Human Swiss Prot No:
Q15761Mouse Gene Id:
18168Mouse Swiss Prot No:
O70342Rat Gene Id:
25340Rat Swiss Prot No:
Q63634Specificity:
NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
NPY5R; NPYR5; Neuropeptide Y receptor type 5; NPY5-R; NPY-Y5 receptor; NPYY5-R; Y5 receptorObserved Band(KD):
48Background:
neuropeptide Y receptor Y5(NPY5R) Homo sapiens The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015],Function:
function:Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Brain; hypothalamus.,Subcellular Location:
Cell membrane; Multi-pass membrane protein.Expression:
Brain; hypothalamus.
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