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NPY1-R Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-73183

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human NPY1R. AA range:221-270

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of 3T3 cells using NPY1-R Polyclonal Antibody

  • Gene Name:

    NPY1R

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Background:

    neuropeptide Y receptor Y1(NPY1R) Homo sapiens This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013],

  • Protein Name:

    Neuropeptide Y receptor type 1

  • Human Gene Id:

    4886

  • Human Swiss Prot No:

    P25929

  • Mouse Gene Id:

    18166

  • Mouse Swiss Prot No:

    Q04573

  • Rat Swiss Prot No:

    P21555

  • Specificity:

    NPY1-R Polyclonal Antibody detects endogenous levels of NPY1-R protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    NPY1R; NPYR; NPYY1; Neuropeptide Y receptor type 1; NPY1-R

  • MolecularWeight(Da):

    44392

  • Observed Band(KD):

    48

  • Function:

    function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,

  • Subcellular Location:

    plasma membrane,integral component of plasma membrane,integral component of membrane,

  • Expression:

    Blood,Brain,Pancreas,Testis,

  • Western blot analysis of lysates from NIH/3T3 cells, using NPY1R Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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NPY1-R Polyclonal Antibody | EnoGene Biotech Co. Ltd