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NK-3R Polyclonal Antibody
Datasheet
Catalog Number:
E20-73133Amount:
100ulMolecular Weight:
52202DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human NK3R. AA range:401-450Source:
Polyclonal, Rabbit
- Western Blot analysis of COLO205 cells using NK-3R Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit
Gene Name:
TACR3Dilution:
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Neuromedin-K receptorHuman Gene Id:
6870Human Swiss Prot No:
P29371Mouse Gene Id:
21338Mouse Swiss Prot No:
P47937Rat Gene Id:
24808Rat Swiss Prot No:
P16177Specificity:
NK-3R Polyclonal Antibody detects endogenous levels of NK-3R protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
TACR3; NK3R; TAC3R; Neuromedin-K receptor; NKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3Observed Band(KD):
52Background:
tachykinin receptor 3(TACR3) Homo sapiens This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008],Function:
function:This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.,PTM:The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.,similarity:Belongs to the G-protein coupled receptor 1 family.,Subcellular Location:
Cell membrane; Multi-pass membrane protein.Expression:
Brain,G-protein coupled receptors,PCR rescued clones,Placenta,
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