NHE-6 Polyclonal Antibody

Name: NHE-6 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-73117
Price: 225 USD
Availability: InStock

E20-73117Cite ID: EN0053250Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight74162 Da

Protein NameSodium/hydrogen exchanger 6

Human Gene Id10479

Human Swiss Prot NoQ92581

SpecificityNHE-6 Polyclonal Antibody detects endogenous levels of NHE-6 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSLC9A6; KIAA0267; NHE6; Sodium/hydrogen exchanger 6; Na(+)/H(+) exchanger 6; NHE-6; Solute carrier family 9 member 6

Observed Band(KD)75

Functioncaution:Was initially identified as a mitochondrial inner membrane protein (PubMed:9507001), but was later shown to be localized in early and recycling endosomes and not mitochondria (PubMed:11940519).,disease:Defects in SLC9A6 are the cause of mental retardation syndromic X-linked Christianson type (MRXSC) [MIM:300243]; also known as MRXS-Christianson or X-linked Angelman-like syndrome. The phenotype is characterized by profound mental retardation, epilepsy, ataxia, and microcephaly, and showed phenotypic overlap with Angelman syndrome.,function:Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subcellular location:Is present in the recycling compartments including early and recycling endosomes,

Subcellular Locationmitochondrion,late endosome,endoplasmic reticulum membrane,plasma membrane,integral component of membrane,dendrite,cytoplasmic vesicle,early endosome membrane,intracellular membrane-bounded organelle,axon terminus,axonal sp

ExpressionBone marrow,Brain,Liver,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human SLC9A6. AA range:551-600

Gene NameSLC9A6

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Backgroundsolute carrier family 9 member A6(SLC9A6) Homo sapiens This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-73117-Conjugate. Price: $485 / Size: 100μl.

E20-73117-FITC$485 / 100μlE20-73117-Biotin$485 / 100μlE20-73117-HRP$485 / 100μlE20-73117-AP$485 / 100μlE20-73117-AF350$485 / 100μlE20-73117-AF405M$485 / 100μlE20-73117-AF488$485 / 100μlE20-73117-AF514$485 / 100μlE20-73117-AF532$485 / 100μlE20-73117-AF555$485 / 100μlE20-73117-AF568$485 / 100μlE20-73117-AF405S$485 / 100μlE20-73117-AF405L$485 / 100μlE20-73117-AF546$485 / 100μlE20-73117-AF594$485 / 100μlE20-73117-AF610$485 / 100μlE20-73117-AF635$485 / 100μlE20-73117-AF647$485 / 100μlE20-73117-AF680$485 / 100μlE20-73117-AF700$485 / 100μlE20-73117-AF750$485 / 100μlE20-73117-AF790$485 / 100μlE20-73117-APC$485 / 100μlE20-73117-PE$485 / 100μlE20-73117-Cy3$485 / 100μlE20-73117-Cy5$485 / 100μlE20-73117-Cy5.5$485 / 100μlE20-73117-Cy7$485 / 100μlE20-73117-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.