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NGEP Polyclonal Antibody
Datasheet
Catalog Number:
E20-73113Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human TM16G. AA range:881-930Source:
Polyclonal, Rabbit
- Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using TM16G Antibody. The picture on the right is blocked with the synthesized peptide.
Gene Name:
ANO7Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Background:
anoctamin 7(ANO7) Homo sapiens This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011],Protein Name:
Anoctamin-7Human Gene Id:
50636Human Swiss Prot No:
Q6IWH7Mouse Swiss Prot No:
Q14AT5Specificity:
NGEP Polyclonal Antibody detects endogenous levels of NGEP protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ANO7; NGEP; PCANAP5; TMEM16G; Anoctamin-7; Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16GMolecularWeight(Da):
105531Observed Band(KD):
105Function:
caution:It is uncertain whether Met-1 or Met-55 is the initiator.,function:May act as a calcium-activated chloride channel. May play a role in cell-cell interactions.,induction:Up-regulated by androgen.,similarity:Belongs to the anoctamin family.,subcellular location:Concentrates at sites of cell-cell contact.,tissue specificity:Specifically expressed in epithelial cells of the prostate (at protein level).,Subcellular Location:
intracellular,nucleus,endoplasmic reticulum,cytosol,plasma membrane,integral component of membrane,cell junction,Expression:
Pancreas,
- Western Blot analysis of 3T3 cells using NGEP Polyclonal Antibody diluted at 1:1000
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