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NF-YC Polyclonal Antibody
Datasheet
Catalog Number:
E20-73092Amount:
100ulMolecular Weight:
50302DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human NFYC. AA range:1-50Source:
Polyclonal, Rabbit
- Western Blot analysis of various cells using NF-YC Polyclonal Antibody diluted at 1:1000
Gene Name:
NFYCDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Nuclear transcription factor Y subunit gammaHuman Gene Id:
4802Human Swiss Prot No:
Q13952Mouse Gene Id:
18046Mouse Swiss Prot No:
P70353Rat Gene Id:
25337Rat Swiss Prot No:
Q62725Specificity:
NF-YC Polyclonal Antibody detects endogenous levels of NF-YC protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
NFYC; Nuclear transcription factor Y subunit gamma; CAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2Observed Band(KD):
50Background:
nuclear transcription factor Y subunit gamma(NFYC) Homo sapiens This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],Function:
function:Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.,similarity:Belongs to the NFYC/HAP5 subunit family.,subunit:Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.,Subcellular Location:
Nucleus.Expression:
Brain,Lymph node,Synovial membrane tissue,
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