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Neuronal PAS1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73071Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human NPAS1. AA range:445-494Source:
Polyclonal, RabbitGene Name:
NPAS1Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
- Western blot analysis of NPAS1 Antibody. The lane on the right is blocked with the NPAS1 peptide.
Background:
neuronal PAS domain protein 1(NPAS1) Homo sapiens The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008],Protein Name:
Neuronal PAS domain-containing protein 1Human Gene Id:
4861Human Swiss Prot No:
Q99742Mouse Swiss Prot No:
P97459Specificity:
Neuronal PAS1 Polyclonal Antibody detects endogenous levels of Neuronal PAS1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
NPAS1; BHLHE11; MOP5; PASD5; Neuronal PAS domain-containing protein 1; Neuronal PAS1; Basic-helix-loop-helix-PAS protein MOP5; Class E basic helix-loop-helix protein 11; bHLHe11; Member of PAS protein 5; PAS domain-containing protein 5MolecularWeight(Da):
62702Observed Band(KD):
62Function:
function:May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Interacts with ARNT.,Subcellular Location:
nucleus,Expression:
Brain,Fetal brain,Hepatoma,
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