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Neuromedin-U Polyclonal Antibody
Datasheet
Catalog Number:
E20-73068Amount:
100ulMolecular Weight:
19741DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human NMU. AA range:125-174Source:
Polyclonal, Rabbit
- Western Blot analysis of various cells using Neuromedin-U Polyclonal Antibody diluted at 1:500
Gene Name:
NMUDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Neuromedin-UHuman Gene Id:
10874Human Swiss Prot No:
P48645Mouse Swiss Prot No:
Q9QXK8Specificity:
Neuromedin-U Polyclonal Antibody detects endogenous levels of Neuromedin-U protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
NMU; Neuromedin-UObserved Band(KD):
22Background:
neuromedin U(NMU) Homo sapiens This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015],Function:
function:Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.,similarity:Belongs to the NmU family.,tissue specificity:Expressed throughout the enteric nervous system with highest levels being found in the jejunum.,Subcellular Location:
Secreted.Expression:
Expressed throughout the enteric nervous system with highest levels being found in the jejunum.
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