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Nesprin-3 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73039Amount:
100ulReactivity:
Human,MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen..Immunogen:
The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218Source:
Polyclonal, Rabbit
- Western Blot analysis of Jurkat cells using Nesprin-3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Gene Name:
SYNE3Dilution:
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Nesprin-3Human Gene Id:
161176Human Swiss Prot No:
Q6ZMZ3Specificity:
Nesprin-3 Polyclonal Antibody detects endogenous levels of Nesprin-3 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3MolecularWeight: 112216DaObserved Band(KD):
130Background:
function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin.,Function:
function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin.,Subcellular Location:
nuclear envelope,nuclear outer membrane,rough endoplasmic reticulum,membrane,integral component of membrane,LINC complex,
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