Product Information
Molecular Weight66951Da
Protein NameSodium/potassium/calcium exchanger 4
Human Gene Id123041
Human Swiss Prot NoQ8NFF2
Mouse Gene Id238384
Mouse Swiss Prot NoQ8CGQ8
SpecificityNCKX4 Polyclonal Antibody detects endogenous levels of NCKX4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC24A4; NCKX4; Sodium/potassium/calcium exchanger 4; Na(+)/K(+)/Ca(2+)-exchange protein 4; Solute carrier family 24 member 4
Observed Band(KD)60
Functioncaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,polymorphism:Genetic variations in SLC24A4 are associated with skin/hair/eye pigmentation type 6 (SHEP6) [MIM:210750]. Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation, with a broad normal range that is subject to substantial geographic stratification. In the case of skin, individuals tend to have lighter pigmentation with increasing distance from the equator. By contrast, the majority of variation in human eye and hair color is found among individuals of European ancestry, with most other human populations fixed for brown eyes and black hair.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,tissue specifici
Subcellular Locationcytoplasm,plasma membrane,integral component of plasma membrane,membrane,
ExpressionTestis,
Backgroundsolute carrier family 24 member 4(SLC24A4) Homo sapiens This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010],