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Nap1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72978Amount:
100ulMolecular Weight:
44935Applications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59Source:
Polyclonal, Rabbit
- Western Blot analysis of various cells using Nap1 Polyclonal Antibody
Gene Name:
AZI2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
5-azacytidine-induced protein 2Human Gene Id:
64343Human Swiss Prot No:
Q9H6S1Mouse Gene Id:
27215Mouse Swiss Prot No:
Q9QYP6Rat Gene Id:
316051Rat Swiss Prot No:
Q4KMA0Specificity:
Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
AZI2; NAP1; 5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILPObserved Band(KD):
48Background:
5-azacytidine induced 2(AZI2) Homo sapiens AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008],Function:
function:Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.,subunit:Interacts with IKBKE, TBK1 and TICAM1.,tissue specificity:Widely expressed. Abundant expression seen in the pancreas and testis.,Subcellular Location:
Cytoplasm .Expression:
Widely expressed (PubMed:14560022). Abundant expression seen in the pancreas and testis (PubMed:14560022).
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