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MRP-S27 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72884Amount:
100ulMolecular Weight:
47669DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MRPS27. AA range:16-65Source:
Polyclonal, Rabbit
- Western Blot analysis of various cells using MRP-S27 Polyclonal Antibody
Gene Name:
MRPS27Dilution:
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000Protein Name:
28S ribosomal protein S27 mitochondrialHuman Gene Id:
23107Human Swiss Prot No:
Q92552Mouse Swiss Prot No:
Q8BK72Specificity:
MRP-S27 Polyclonal Antibody detects endogenous levels of MRP-S27 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
MRPS27; KIAA0264; 28S ribosomal protein S27; mitochondrial; MRP-S27; S27mtObserved Band(KD):
48Background:
mitochondrial ribosomal protein S27(MRPS27) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013],Function:
similarity:Contains 2 PPR (pentatricopeptide) repeats.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,Subcellular Location:
Cytoplasm . Mitochondrion .Expression:
Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level) (PubMed:28714366). Ubiquitous (PubMed:22841715).
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