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MRP-S17 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72876Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MRPS17. AA range:11-60Source:
Polyclonal, RabbitGene Name:
MRPS17Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
- Western blot analysis of lysates from NIH/3T3, RAW264.7, and A549 cells, using MRPS17 Antibody. The lane on the right is blocked with the synthesized peptide.
Background:
mitochondrial ribosomal protein S17(MRPS17) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are foundProtein Name:
28S ribosomal protein S17 mitochondrialHuman Gene Id:
51373Human Swiss Prot No:
Q9Y2R5Mouse Gene Id:
66258Mouse Swiss Prot No:
Q9CQE3Specificity:
MRP-S17 Polyclonal Antibody detects endogenous levels of MRP-S17 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
MRPS17; RPMS17; HSPC011; 28S ribosomal protein S17; mitochondrial; MRP-S17; S17mtMolecularWeight(Da):
14502Observed Band(KD):
22Function:
similarity:Belongs to the ribosomal protein S17P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,Subcellular Location:
mitochondrial inner membrane,mitochondrial small ribosomal subunit,ribosome,Expression:
Brain,Epithelium,Kidney,Umbilical cord blood,Uterus,
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