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MRP-S12 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72874Amount:
100ulMolecular Weight:
15173DaPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MRPS12. AA range:21-70Source:
Polyclonal, Rabbit
- Western Blot analysis of SH-SY5Y cells using MRP-S12 Polyclonal Antibody diluted at 1:1000
Gene Name:
MRPS12Dilution:
WB 1:500-2000;IHC-p 1:50-300Protein Name:
28S ribosomal protein S12 mitochondrialHuman Gene Id:
6183Human Swiss Prot No:
O15235Mouse Gene Id:
24030Mouse Swiss Prot No:
O35680Specificity:
MRP-S12 Polyclonal Antibody detects endogenous levels of MRP-S12 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
MRPS12; RPMS12; RPSM12; 28S ribosomal protein S12; mitochondrial; MRP-S12; S12mt; MT-RPS12Observed Band(KD):
20Background:
mitochondrial ribosomal protein S12(MRPS12) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. ThFunction:
similarity:Belongs to the ribosomal protein S12P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,Subcellular Location:
Mitochondrion .Expression:
Brain,Colon,Liver,Skin,
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