Product Information
Molecular Weight13664Da
Protein Name39S ribosomal protein L52 mitochondrial
Human Gene Id122704
Human Swiss Prot NoQ86TS9
Mouse Swiss Prot NoQ9D0Y8
SpecificityMRP-L52 Polyclonal Antibody detects endogenous levels of MRP-L52 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameMRPL52; 39S ribosomal protein L52; mitochondrial; L52mt; MRP-L52
Functionsubunit:Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.,
Subcellular Locationmitochondrial inner membrane,mitochondrial large ribosomal subunit,
ExpressionBrain,Placenta,
Backgroundmitochondrial ribosomal protein L52(MRPL52) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008],