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MRP-L40 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72862Amount:
100ulMolecular Weight:
(Da):24490Applications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MRPL40. AA range:101-150Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using MRP-L40 Polyclonal Antibody diluted at 1:1000
Gene Name:
MRPL40Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
39S ribosomal protein L40 mitochondrialHuman Gene Id:
64976Human Swiss Prot No:
Q9NQ50Mouse Swiss Prot No:
Q9Z2Q5Specificity:
MRP-L40 Polyclonal Antibody detects endogenous levels of MRP-L40 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
MRPL40; NLVCF; URIM; 39S ribosomal protein L40; mitochondrial; L40mt; MRP-L40; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Up-regulated in metastasisObserved Band(KD):
24Background:
mitochondrial ribosomal protein L40(MRPL40) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008],Function:
tissue specificity:Ubiquitous.,Subcellular Location:
Mitochondrion .Expression:
Ubiquitous.
- Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using MRPL40 Antibody. The picture on the right is blocked with the synthesized peptide.
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