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MRP-L12 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72845Amount:
100ulMolecular Weight:
21348DaApplications:
WB;ELISA;IHC-pReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MRPL12. AA range:31-80Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using MRP-L12 Polyclonal Antibody
Gene Name:
MRPL12Dilution:
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000Protein Name:
39S ribosomal protein L12 mitochondrialHuman Gene Id:
6182Human Swiss Prot No:
P52815Mouse Gene Id:
56282Mouse Swiss Prot No:
Q9DB15Specificity:
MRP-L12 Polyclonal Antibody detects endogenous levels of MRP-L12 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
MRPL12; RPML12; 39S ribosomal protein L12; mitochondrial; L12mt; MRP-L12; 5c5-2Observed Band(KD):
21Background:
mitochondrial ribosomal protein L12(MRPL12) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008],Function:
similarity:Belongs to the ribosomal protein L12P family.,Subcellular Location:
Mitochondrion .Expression:
Muscle,Tonsil,
- Western blot analysis of lysates from COLO cells, using MRPL12 Antibody. The lane on the right is blocked with the synthesized peptide.
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