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MRP7 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72842Amount:
100ulMolecular Weight:
161629DaApplications:
WB;IHC-pReactivity:
Human;MonkeyPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MRP7. AA range:835-884Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using MRP7 Polyclonal Antibody diluted at 1:1000
Gene Name:
ABCC10Dilution:
WB 1:500-2000;IHC-p 1:50-300Protein Name:
Multidrug resistance-associated protein 7Human Gene Id:
89845Human Swiss Prot No:
Q5T3U5Mouse Swiss Prot No:
Q8R4P9Specificity:
MRP7 Polyclonal Antibody detects endogenous levels of MRP7 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ABCC10; MRP7; SIMRP7; Multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10Observed Band(KD):
162Background:
ATP binding cassette subfamily C member 10(ABCC10) Homo sapiens The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010],Function:
function:ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily.,similarity:Contains 2 ABC transmembrane type-1 domains.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.,Subcellular Location:
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein .Expression:
[Isoform 1]: Specifically expressed in spleen. ; [Isoform 2]: Widely expressed.
- Western Blot analysis of COS7 cells using MRP7 Polyclonal Antibody diluted at 1:1000
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