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Cell Signal Transduction Research Antibodies
MKP-5 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight52642DaObserved Band:52KD
Protein NameDual specificity protein phosphatase 10
Human Gene Id11221
Human Swiss Prot NoQ9Y6W6
Mouse Gene Id63953
Mouse Swiss Prot NoQ9ESS0
SpecificityMKP-5 Polyclonal Antibody detects endogenous levels of MKP-5 protein
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDUSP10; MKP5; Dual specificity protein phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5
Functioncatalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
Subcellular Locationnucleus,nucleoplasm,cytoplasm,Golgi apparatus,
ExpressionBrain,Epithelium,Lung,PNS,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from MKP-5 . at AA range: 330-410
Gene NameDUSP10
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Backgrounddual specificity phosphatase 10(DUSP10) Homo sapiens Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-72776-Conjugate. Price: $485 / Size: 100μl.
E20-72776-FITC$485 / 100μlE20-72776-Biotin$485 / 100μlE20-72776-HRP$485 / 100μlE20-72776-AP$485 / 100μlE20-72776-AF350$485 / 100μlE20-72776-AF405M$485 / 100μlE20-72776-AF488$485 / 100μlE20-72776-AF514$485 / 100μlE20-72776-AF532$485 / 100μlE20-72776-AF555$485 / 100μlE20-72776-AF568$485 / 100μlE20-72776-AF405S$485 / 100μlE20-72776-AF405L$485 / 100μlE20-72776-AF546$485 / 100μlE20-72776-AF594$485 / 100μlE20-72776-AF610$485 / 100μlE20-72776-AF635$485 / 100μlE20-72776-AF647$485 / 100μlE20-72776-AF680$485 / 100μlE20-72776-AF700$485 / 100μlE20-72776-AF750$485 / 100μlE20-72776-AF790$485 / 100μlE20-72776-APC$485 / 100μlE20-72776-PE$485 / 100μlE20-72776-Cy3$485 / 100μlE20-72776-Cy5$485 / 100μlE20-72776-Cy5.5$485 / 100μlE20-72776-Cy7$485 / 100μlE20-72776-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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