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MIC2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72758Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CD99. AA range:11-60Source:
Polyclonal, RabbitGene Name:
CD99Dilution:
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Immunofluorescence analysis of COS7 cells, using CD99 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
CD99 molecule(CD99) Homo sapiens The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016],Protein Name:
CD99 antigenHuman Gene Id:
4267Human Swiss Prot No:
P14209Mouse Swiss Prot No:
Q8VCN6Specificity:
MIC2 Polyclonal Antibody detects endogenous levels of MIC2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CD99; MIC2; MIC2X; MIC2Y; CD99 antigen; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD antigen CD99MolecularWeight(Da):
18848Function:
function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,Subcellular Location:
cytoplasm,plasma membrane,integral component of plasma membrane,focal adhesion,integral component of membrane,Expression:
Brain,Kidney,Skin,T-cell,Uterus,
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