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MGST3 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72753Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human MGST3. AA range:8-57Source:
Polyclonal, RabbitGene Name:
MGST3Dilution:
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
- Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MGST3 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
microsomal glutathione S-transferase 3(MGST3) Homo sapiens This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011],Protein Name:
Microsomal glutathione S-transferase 3Human Gene Id:
4259Human Swiss Prot No:
O14880Mouse Gene Id:
66447Mouse Swiss Prot No:
Q9CPU4Specificity:
MGST3 Polyclonal Antibody detects endogenous levels of MGST3 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
MGST3; Microsomal glutathione S-transferase 3; Microsomal GST-3; Microsomal GST-IIIMolecularWeight(Da):
16516Function:
catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Also functions as a glutathione peroxidase.,similarity:Belongs to the MAPEG family.,tissue specificity:Predominantly expressed in heart, skeletal muscle, and adrenal cortex. Also found in brain, placenta, liver, kidney, pancreas, thyroid, testis and ovary. Almost absent in lung, thymus and peripheral blood leukocytes.,Subcellular Location:
nuclear envelope,endoplasmic reticulum,endoplasmic reticulum membrane,membrane,integral component of membrane,organelle membrane,intracellular membrane-bounded organelle,extracellular exosome,Expression:
Human small intestine,Kidney,Lung,
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