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MGST1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72751

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human MGST1. AA range:42-91

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    MGST1

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Western blot analysis of lysates from HeLa cells, using MGST1 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Background:

    microsomal glutathione S-transferase 1(MGST1) Homo sapiens The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012],

  • Protein Name:

    Microsomal glutathione S-transferase 1

  • Human Gene Id:

    4257

  • Human Swiss Prot No:

    P10620

  • Mouse Swiss Prot No:

    Q91VS7

  • Specificity:

    MGST1 Polyclonal Antibody detects endogenous levels of MGST1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    MGST1; GST12; MGST; Microsomal glutathione S-transferase 1; Microsomal GST-1; Microsomal GST-I

  • MolecularWeight(Da):

    17599

  • Observed Band(KD):

    18

  • Function:

    catalytic activity:RX + glutathione = HX + R-S-glutathione.,enzyme regulation:Activated by N-ethylmaleimide, except in the testis.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.,similarity:Belongs to the MAPEG family.,subunit:Homotrimer.,tissue specificity:Highly expressed in liver.,

  • Subcellular Location:

    nucleus,mitochondrion,mitochondrial outer membrane,mitochondrial inner membrane,peroxisomal membrane,endoplasmic reticulum,endoplasmic reticulum membrane,integral component of membrane,apical part of cell,

  • Expression:

    Foreskin,Liver,Prostate,

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Catalog Number

  • Amount:100ul
  • Price:225$

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MGST1 Polyclonal Antibody | EnoGene Biotech Co. Ltd