MerTK/Tyro3 Polyclonal Antibody

Name: MerTK/Tyro3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-72734
Price: 225 USD
Availability: InStock

E20-72734Cite ID: EN0052867Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight110249/96905 Da

Protein NameTyrosine-protein kinase Mer/Tyrosine-protein kinase receptor TYRO3

Human Gene Id10461/7301

Human Swiss Prot NoQ12866/Q06418

Mouse Gene Id17289/22174

Rat Gene Id65037/25232

Rat Swiss Prot NoP57097/P55146

SpecificityMerTK/Tyro3 Polyclonal Antibody detects endogenous levels of MerTK/Tyro3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameMERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; TYRO3; BYK; DTK; RSE; SKY; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kin

Observed Band(KD)97

Functioncatalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in MERTK are a cause of retinitis pigmentosa (RP) [MIM:268000]. RP that leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.,function:In case of filovirus infection, seems to function as a cell entry factor.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (imm

Subcellular Locationphotoreceptor outer segment,extracellular space,cytoplasm,plasma membrane,integral component of plasma membrane,integral component of membrane,rhabdomere,

ExpressionGastric cancer,PCR rescued clones,Peripheral blood leukocyte,Plasma

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human MER/SKY. AA range:716-765

Gene NameMERTK/TYRO3

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

BackgroundMER proto-oncogene, tyrosine kinase(MERTK) Homo sapiens This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-72734-Conjugate. Price: $485 / Size: 100μl.

E20-72734-FITC$485 / 100μlE20-72734-Biotin$485 / 100μlE20-72734-HRP$485 / 100μlE20-72734-AP$485 / 100μlE20-72734-AF350$485 / 100μlE20-72734-AF405M$485 / 100μlE20-72734-AF488$485 / 100μlE20-72734-AF514$485 / 100μlE20-72734-AF532$485 / 100μlE20-72734-AF555$485 / 100μlE20-72734-AF568$485 / 100μlE20-72734-AF405S$485 / 100μlE20-72734-AF405L$485 / 100μlE20-72734-AF546$485 / 100μlE20-72734-AF594$485 / 100μlE20-72734-AF610$485 / 100μlE20-72734-AF635$485 / 100μlE20-72734-AF647$485 / 100μlE20-72734-AF680$485 / 100μlE20-72734-AF700$485 / 100μlE20-72734-AF750$485 / 100μlE20-72734-AF790$485 / 100μlE20-72734-APC$485 / 100μlE20-72734-PE$485 / 100μlE20-72734-Cy3$485 / 100μlE20-72734-Cy5$485 / 100μlE20-72734-Cy5.5$485 / 100μlE20-72734-Cy7$485 / 100μlE20-72734-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.