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MEL-1B-R Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72727

  • Amount:

    100ul

  • Molecular Weight:

    40188Da

  • Applications:

    WB;IHC-p

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human MTR1B. AA range:301-350

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using MEL-1B-R Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    MTNR1B

  • Dilution:

    WB 1:500-2000;IHC-p 1:50-300

  • Protein Name:

    Melatonin receptor type 1B

  • Human Gene Id:

    4544

  • Human Swiss Prot No:

    P49286

  • Mouse Swiss Prot No:

    Q8CIQ6

  • Specificity:

    MEL-1B-R Polyclonal Antibody detects endogenous levels of MEL-1B-R protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    MTNR1B; Melatonin receptor type 1B; Mel-1B-R; Mel1b receptor

  • Observed Band(KD):

    40

  • Background:

    This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008],

  • Function:

    function:High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.,online information:Melatonin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in retina and less in brain and hippocampus.,

  • Subcellular Location:

    Cell membrane; Multi-pass membrane protein.

  • Expression:

    Expressed in retina and less in brain and hippocampus.

  • Western Blot analysis of various cells using MEL-1B-R Polyclonal Antibody diluted at 1:1000

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Catalog Number

  • Amount:100ul
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MEL-1B-R Polyclonal Antibody | EnoGene Biotech Co. Ltd