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MEF-2B Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72701

  • Amount:

    100ul

  • Molecular Weight:

    38639Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human MEF2B. AA range:51-100

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using MEF-2B Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

  • Gene Name:

    MEF2B

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Myocyte-specific enhancer factor 2B

  • Human Gene Id:

    4207

  • Human Swiss Prot No:

    Q02080

  • Mouse Swiss Prot No:

    O55087

  • Specificity:

    MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    MEF2B; XMEF2; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2

  • Observed Band(KD):

    38

  • Background:

    This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010],

  • Function:

    function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.,similarity:Belongs to the MEF2 family.,similarity:Contains 1 MADS-box domain.,similarity:Contains 1 Mef2-type DNA-binding domain.,subunit:Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.,tissue specificity:Expressed in skeletal and cardiac muscle and brain.,

  • Subcellular Location:

    Nucleus.

  • Expression:

    Expressed in skeletal and cardiac muscle and brain.

  • Western blot analysis of lysates from HT-29 cells, using MEF2B Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

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MEF-2B Polyclonal Antibody | EnoGene Biotech Co. Ltd