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Cell Signal Transduction Research Antibodies
ME3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight67054Da
Protein NameNADP-dependent malic enzyme mitochondrial
Human Gene Id10873
Human Swiss Prot NoQ16798
Mouse Gene Id109264
Mouse Swiss Prot NoQ8BMF3
SpecificityME3 Polyclonal Antibody detects endogenous levels of ME3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameME3; NADP-dependent malic enzyme; mitochondrial; NADP-ME; Malic enzyme 3
Observed Band(KD)67
Functioncatalytic activity:(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,similarity:Belongs to the malic enzymes family.,tissue specificity:Expressed predominantly in organs with a low-division rate.,
Subcellular Locationmitochondrion,mitochondrial matrix,plasma membrane,
ExpressionBrain,Hippocampus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ME3. AA range:545-594
Gene NameME3
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Backgroundmalic enzyme 3(ME3) Homo sapiens Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-72695-Conjugate. Price: $485 / Size: 100μl.
E20-72695-FITC$485 / 100μlE20-72695-Biotin$485 / 100μlE20-72695-HRP$485 / 100μlE20-72695-AP$485 / 100μlE20-72695-AF350$485 / 100μlE20-72695-AF405M$485 / 100μlE20-72695-AF488$485 / 100μlE20-72695-AF514$485 / 100μlE20-72695-AF532$485 / 100μlE20-72695-AF555$485 / 100μlE20-72695-AF568$485 / 100μlE20-72695-AF405S$485 / 100μlE20-72695-AF405L$485 / 100μlE20-72695-AF546$485 / 100μlE20-72695-AF594$485 / 100μlE20-72695-AF610$485 / 100μlE20-72695-AF635$485 / 100μlE20-72695-AF647$485 / 100μlE20-72695-AF680$485 / 100μlE20-72695-AF700$485 / 100μlE20-72695-AF750$485 / 100μlE20-72695-AF790$485 / 100μlE20-72695-APC$485 / 100μlE20-72695-PE$485 / 100μlE20-72695-Cy3$485 / 100μlE20-72695-Cy5$485 / 100μlE20-72695-Cy5.5$485 / 100μlE20-72695-Cy7$485 / 100μlE20-72695-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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