Product Information
Molecular Weight42138 DaObserved Band:40 KD
Protein NameSerpin B5
Human Gene Id5268
Human Swiss Prot NoP36952
Mouse Gene Id20724
Mouse Swiss Prot NoP70124
Rat Gene Id116589
Rat Swiss Prot NoP70564
SpecificityMaspin Polyclonal Antibody detects endogenous levels of Maspin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSERPINB5; PI5; Serpin B5; Maspin; Peptidase inhibitor 5; PI-5
Functionfunction:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
Subcellular LocationSecreted, extracellular space.
ExpressionNormal mammary epithelial cells..
Backgroundfunction:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,