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Mash2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72655Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
Synthesized peptide derived from Mash2 . at AA range: 1-80Source:
Polyclonal, RabbitGene Name:
ASCL2Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
Background:
achaete-scute family bHLH transcription factor 2(ASCL2) Homo sapiens This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008],Protein Name:
Achaete-scute homolog 2Human Gene Id:
430Human Swiss Prot No:
Q99929Mouse Gene Id:
17173Mouse Swiss Prot No:
O35885Rat Gene Id:
24209Rat Swiss Prot No:
P19360Specificity:
Mash2 Polyclonal Antibody detects endogenous levels of Mash2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ASCL2; BHLHA45; HASH2; Achaete-scute homolog 2; ASH-2; hASH2; Class A basic helix-loop-helix protein 45; bHLHa45; Mash2MolecularWeight(Da):
20185Observed Band(KD):
25Function:
function:AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Expressed specifically in the extravillous trophoblasts of the developing placenta.,Subcellular Location:
nucleus,cytoplasm,RNA polymerase II transcription factor complex,
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