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MARK1/2/3/4 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72649

  • Amount:

    100ul

  • Molecular Weight:

    89003 DaObserved Band:89 KD

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human MARK. AA range:121-170

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using MARK1/2/3/4 Polyclonal Antibody diluted at 1:2000

  • Gene Name:

    MARK1/2/3/4

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Serine/threonine-protein kinase MARK1/2/3/4

  • Human Gene Id:

    4139/2011/4140/57787

  • Human Swiss Prot No:

    Q9P0L2/Q7KZI7/P27448/Q96L34

  • Mouse Gene Id:

    226778/13728/17169/232944

  • Rat Gene Id:

    117016/60328/170577

  • Rat Swiss Prot No:

    O08678/O08679/Q8VHF0

  • Specificity:

    MARK1/2/3/4 Polyclonal Antibody detects endogenous levels of MARK1/2/3/4 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin

  • Background:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in cytoskeletal stability.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,

  • Function:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in cytoskeletal stability.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,

  • Subcellular Location:

    Cell membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm . Cell projection, dendrite . Appears to localize to an intracellular network. .

  • Expression:

    Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.

  • Western blot analysis of lysates from HeLa cells, using MARK Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
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MARK1/2/3/4 Polyclonal Antibody | EnoGene Biotech Co. Ltd