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Cell Signal Transduction Research Antibodies
MARCH3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight28504DaObserved Band:29KD
Protein NameE3 ubiquitin-protein ligase MARCH3
Human Gene Id115123
Human Swiss Prot NoQ86UD3
Mouse Gene Id320253
Mouse Swiss Prot NoQ8BRX9
Rat Gene Id364878
Rat Swiss Prot NoQ5XIE5
SpecificityMARCH3 Polyclonal Antibody detects endogenous levels of 40605 protein
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameMARCH3; RNF173; E3 ubiquitin-protein ligase MARCH3; Membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; MARCH-III; RING finger protein 173
Functiondomain:The RING-CH-type zinc finger domain is required for E3 ligase activity.,function:E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 RING-CH-type zinc finger.,subunit:Interacts with MARCH2 and STX6.,
Subcellular Locationlysosome,endosome,integral component of membrane,cytoplasmic vesicle membrane,early endosome membrane,
ExpressionBrain,Thalamus,,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human MARCH3. AA range:111-160
Gene NameMARCH3
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Backgroundmembrane associated ring-CH-type finger 3(MARCH3) Homo sapiens This gene encodes a member of the membrane-associated RING-CH (MARCH) family. The encoded protein is an E3 ubiquitin-protein ligase that may be involved in regulation of the endosomal transport pathway. [provided by RefSeq, Mar 2013],
Conjugated Antibody
This product is also available conjugated. Format: E20-72644-Conjugate. Price: $485 / Size: 100μl.
E20-72644-FITC$485 / 100μlE20-72644-Biotin$485 / 100μlE20-72644-HRP$485 / 100μlE20-72644-AP$485 / 100μlE20-72644-AF350$485 / 100μlE20-72644-AF405M$485 / 100μlE20-72644-AF488$485 / 100μlE20-72644-AF514$485 / 100μlE20-72644-AF532$485 / 100μlE20-72644-AF555$485 / 100μlE20-72644-AF568$485 / 100μlE20-72644-AF405S$485 / 100μlE20-72644-AF405L$485 / 100μlE20-72644-AF546$485 / 100μlE20-72644-AF594$485 / 100μlE20-72644-AF610$485 / 100μlE20-72644-AF635$485 / 100μlE20-72644-AF647$485 / 100μlE20-72644-AF680$485 / 100μlE20-72644-AF700$485 / 100μlE20-72644-AF750$485 / 100μlE20-72644-AF790$485 / 100μlE20-72644-APC$485 / 100μlE20-72644-PE$485 / 100μlE20-72644-Cy3$485 / 100μlE20-72644-Cy5$485 / 100μlE20-72644-Cy5.5$485 / 100μlE20-72644-Cy7$485 / 100μlE20-72644-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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