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MAP-4 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72637

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human MAP4. AA range:662-711

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    MAP4

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Immunofluorescence analysis of HeLa cells, using MAP4 Antibody. The picture on the right is blocked with the synthesized peptide.

  • Background:

    microtubule associated protein 4(MAP4) Homo sapiens The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

  • Protein Name:

    Microtubule-associated protein 4

  • Human Gene Id:

    4134

  • Human Swiss Prot No:

    P27816

  • Mouse Gene Id:

    17758

  • Mouse Swiss Prot No:

    P27546

  • Rat Gene Id:

    367171

  • Rat Swiss Prot No:

    Q5M7W5

  • Specificity:

    MAP-4 Polyclonal Antibody detects endogenous levels of MAP-4 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    MAP4; Microtubule-associated protein 4; MAP-4

  • MolecularWeight(Da):

    121019

  • Function:

    alternative products:Additional isoforms seem to exist,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Non-neuronal microtubule-associated protein. Promotes microtubule assembly.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats.,

  • Subcellular Location:

    cytoplasm,microtubule,microtubule associated complex,plasma membrane,axoneme,postsynaptic density,microtubule cytoskeleton,neuron projection,extracellular exosome,mitotic spindle,

  • Expression:

    Bone marrow,Brain,Cerebellum,Colon carcinoma,Epithelium,Eye,Heart,Liver,Lym

  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MAP4 Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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MAP-4 Polyclonal Antibody | EnoGene Biotech Co. Ltd