MALT1 Polyclonal Antibody

Name: MALT1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-72630
Price: 225 USD
Availability: InStock

E20-72630Cite ID: EN0052763Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight92272Da

Protein NameMucosa-associated lymphoid tissue lymphoma translocation protein 1

Human Gene Id10892

Human Swiss Prot NoQ9UDY8

Mouse Gene Id240354

Mouse Swiss Prot NoQ2TBA3

SpecificityMALT1 Polyclonal Antibody detects endogenous levels of MALT1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameMALT1; MLT; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; Paracaspase

Observed Band(KD)90

Functiondisease:A chromosomal aberration involving MALT1 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with BIRC2. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.,function:Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL-10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.,similarity:Belongs to the peptidase C14B family.,similarity:Contains 1 death domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.,subunit:Binds through its Ig-like

Subcellular Locationnucleus,nucleolus,cytoplasm,cytosol,plasma membrane,CBM complex,protein complex,perinuclear region of cytoplasm,

ExpressionB-cell,Kidney,Testis,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human MALT1. AA range:301-350

Gene NameMALT1

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

BackgroundMALT1 paracaspase(MALT1) Homo sapiens This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-72630-Conjugate. Price: $485 / Size: 100μl.

E20-72630-FITC$485 / 100μlE20-72630-Biotin$485 / 100μlE20-72630-HRP$485 / 100μlE20-72630-AP$485 / 100μlE20-72630-AF350$485 / 100μlE20-72630-AF405M$485 / 100μlE20-72630-AF488$485 / 100μlE20-72630-AF514$485 / 100μlE20-72630-AF532$485 / 100μlE20-72630-AF555$485 / 100μlE20-72630-AF568$485 / 100μlE20-72630-AF405S$485 / 100μlE20-72630-AF405L$485 / 100μlE20-72630-AF546$485 / 100μlE20-72630-AF594$485 / 100μlE20-72630-AF610$485 / 100μlE20-72630-AF635$485 / 100μlE20-72630-AF647$485 / 100μlE20-72630-AF680$485 / 100μlE20-72630-AF700$485 / 100μlE20-72630-AF750$485 / 100μlE20-72630-AF790$485 / 100μlE20-72630-APC$485 / 100μlE20-72630-PE$485 / 100μlE20-72630-Cy3$485 / 100μlE20-72630-Cy5$485 / 100μlE20-72630-Cy5.5$485 / 100μlE20-72630-Cy7$485 / 100μlE20-72630-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.