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Cell Signal Transduction Research Antibodies
mAChR M5 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight60074DaObserved Band:60KD
Protein NameMuscarinic acetylcholine receptor M5
Human Gene Id1133
Human Swiss Prot NoP08912
Mouse Swiss Prot NoQ920H4
SpecificitymAChR M5 Polyclonal Antibody detects endogenous levels of mAChR M5 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCHRM5; Muscarinic acetylcholine receptor M5
Functionfunction:The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Locationplasma membrane,integral component of plasma membrane,cell junction,synapse,postsynaptic membrane,
ExpressionBrain,Keratinocyte,Lens epithelium,Placenta,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CHRM5. AA range:281-330
Gene NameCHRM5
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundcholinergic receptor muscarinic 5(CHRM5) Homo sapiens The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-72614-Conjugate. Price: $485 / Size: 100μl.
E20-72614-FITC$485 / 100μlE20-72614-Biotin$485 / 100μlE20-72614-HRP$485 / 100μlE20-72614-AP$485 / 100μlE20-72614-AF350$485 / 100μlE20-72614-AF405M$485 / 100μlE20-72614-AF488$485 / 100μlE20-72614-AF514$485 / 100μlE20-72614-AF532$485 / 100μlE20-72614-AF555$485 / 100μlE20-72614-AF568$485 / 100μlE20-72614-AF405S$485 / 100μlE20-72614-AF405L$485 / 100μlE20-72614-AF546$485 / 100μlE20-72614-AF594$485 / 100μlE20-72614-AF610$485 / 100μlE20-72614-AF635$485 / 100μlE20-72614-AF647$485 / 100μlE20-72614-AF680$485 / 100μlE20-72614-AF700$485 / 100μlE20-72614-AF750$485 / 100μlE20-72614-AF790$485 / 100μlE20-72614-APC$485 / 100μlE20-72614-PE$485 / 100μlE20-72614-Cy3$485 / 100μlE20-72614-Cy5$485 / 100μlE20-72614-Cy5.5$485 / 100μlE20-72614-Cy7$485 / 100μlE20-72614-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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