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Cell Signal Transduction Research Antibodies
mAChR M1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight51421DaObserved Band:85KD
Protein NameMuscarinic acetylcholine receptor M1
Human Gene Id1128
Human Swiss Prot NoP11229
Mouse Gene Id12669
Mouse Swiss Prot NoP12657
Rat Gene Id25229
Rat Swiss Prot NoP08482
SpecificitymAChR M1 Polyclonal Antibody detects endogenous levels of mAChR M1 protein
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCHRM1; Muscarinic acetylcholine receptor M1
Functionfunction:The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with GPRASP2.,
Subcellular Locationplasma membrane,integral component of plasma membrane,postsynaptic density,membrane,cell junction,dendrite,asymmetric synapse,axon terminus,synapse,postsynaptic membrane,
ExpressionAmygdala,Brain,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CHRM1. AA range:295-344
Gene NameCHRM1
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundcholinergic receptor muscarinic 1(CHRM1) Homo sapiens The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-72611-Conjugate. Price: $485 / Size: 100μl.
E20-72611-FITC$485 / 100μlE20-72611-Biotin$485 / 100μlE20-72611-HRP$485 / 100μlE20-72611-AP$485 / 100μlE20-72611-AF350$485 / 100μlE20-72611-AF405M$485 / 100μlE20-72611-AF488$485 / 100μlE20-72611-AF514$485 / 100μlE20-72611-AF532$485 / 100μlE20-72611-AF555$485 / 100μlE20-72611-AF568$485 / 100μlE20-72611-AF405S$485 / 100μlE20-72611-AF405L$485 / 100μlE20-72611-AF546$485 / 100μlE20-72611-AF594$485 / 100μlE20-72611-AF610$485 / 100μlE20-72611-AF635$485 / 100μlE20-72611-AF647$485 / 100μlE20-72611-AF680$485 / 100μlE20-72611-AF700$485 / 100μlE20-72611-AF750$485 / 100μlE20-72611-AF790$485 / 100μlE20-72611-APC$485 / 100μlE20-72611-PE$485 / 100μlE20-72611-Cy3$485 / 100μlE20-72611-Cy5$485 / 100μlE20-72611-Cy5.5$485 / 100μlE20-72611-Cy7$485 / 100μlE20-72611-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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