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LUC7L2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-72603Amount:
100ulMolecular Weight:
46514 DaObserved Band:47 KDApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human LUC7L2. AA range:129-178Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using LUC7L2 Polyclonal Antibody
Gene Name:
LUC7L2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Putative RNA-binding protein Luc7-like 2Human Gene Id:
51631Human Swiss Prot No:
Q9Y383Mouse Gene Id:
192196Mouse Swiss Prot No:
Q7TNC4Specificity:
LUC7L2 Polyclonal Antibody detects endogenous levels of LUC7L2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
LUC7L2; CGI-59; CGI-74; Putative RNA-binding protein Luc7-like 2Background:
This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],Function:
function:May bind to RNA via its Arg/Ser-rich domain.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Luc7 family.,similarity:Contains 1 C2H2-type zinc finger.,Subcellular Location:
Nucleus speckle . Nucleus, nucleoplasm . Colocalizes with SCNM1 and SNRNP70 in nuclear speckles. .Expression:
Brain,Epithelium,Skin,Uterus,.
- Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using LUC7L2 Antibody. The picture on the right is blocked with the synthesized peptide.
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