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LPCAT2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72585

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human LPCAT2. AA range:321-370

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    LPCAT2

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Western blot analysis of lysates from K562 and HT-29 cells, using LPCAT2 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Background:

    lysophosphatidylcholine acyltransferase 2(LPCAT2) Homo sapiens This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009],

  • Protein Name:

    Lysophosphatidylcholine acyltransferase 2

  • Human Gene Id:

    54947

  • Human Swiss Prot No:

    Q7L5N7

  • Mouse Gene Id:

    270084

  • Mouse Swiss Prot No:

    Q8BYI6

  • Rat Swiss Prot No:

    P0C1Q3

  • Specificity:

    LPCAT2 Polyclonal Antibody detects endogenous levels of LPCAT2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    LPCAT2; AYTL1; Lysophosphatidylcholine acyltransferase 2; LPC acyltransferase 2; LPCAT-2; LysoPC acyltransferase 2; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; Acetyl-CoA:lyso-platelet-ac

  • MolecularWeight(Da):

    60208

  • Observed Band(KD):

    50

  • Function:

    catalytic activity:Acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine.,catalytic activity:Acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine.,domain:The HXXXXD motif is essential for acyltransferase activity.,enzyme regulation:Acetyltransferase activity is increased following acute inflammatory stimulation by lipopolysaccharide (LPS). Acyltransferase activity is unchanged.,function:Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF pre

  • Subcellular Location:

    Golgi membrane,endoplasmic reticulum,endoplasmic reticulum membrane,Golgi stack,lipid particle,integral component of membrane,

  • Expression:

    B-cell,Colon,Skin,

  • Western blot analysis of the lysates from HT-29 cells using LPCAT2 antibody.

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Catalog Number

  • Amount:100ul
  • Price:225$

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LPCAT2 Polyclonal Antibody | EnoGene Biotech Co. Ltd