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LPAAT-δ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72582

  • Amount:

    100ul

  • Molecular Weight:

    44021 DaObserved Band:44 KD

  • Applications:

    WB;IHC-p

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human AGPAT4. AA range:151-200

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using LPAAT-δ Polyclonal Antibody diluted at 1:500

  • Gene Name:

    AGPAT4

  • Dilution:

    WB 1:500-2000;IHC-p 1:50-300

  • Protein Name:

    1-acyl-sn-glycerol-3-phosphate acyltransferase delta

  • Human Gene Id:

    56895

  • Human Swiss Prot No:

    Q9NRZ5

  • Mouse Gene Id:

    68262

  • Mouse Swiss Prot No:

    Q8K4X7

  • Rat Gene Id:

    170919

  • Rat Swiss Prot No:

    Q924S1

  • Specificity:

    LPAAT-δ Polyclonal Antibody detects endogenous levels of LPAAT-δ protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta

  • Background:

    This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008],

  • Function:

    catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,

  • Subcellular Location:

    Endoplasmic reticulum membrane ; Multi-pass membrane protein .

  • Expression:

    Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus..

  • Western blot analysis of lysates from HeLa and MCF-7 cells, using AGPAT4 Antibody. The lane on the right is blocked with the synthesized peptide.

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