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DNA Ligase IV (phospho Thr650) Polyclonal Antibody
Datasheet
Catalog Number:
E20-72559Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
Synthesized peptide derived from the Internal region of human LHX1.Source:
Polyclonal, RabbitGene Name:
LHX1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
- Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
Background:
LIM homeobox 1(LHX1) Homo sapiens This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010],Protein Name:
LIM/homeobox protein Lhx1Human Gene Id:
3975Human Swiss Prot No:
P48742Mouse Gene Id:
16869Mouse Swiss Prot No:
P63006Rat Gene Id:
257634Rat Swiss Prot No:
P63007Specificity:
LHX1 Polyclonal Antibody detects endogenous levels of LHX1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
LHX1; LIM-1; LIM1; LIM/homeobox protein Lhx1; LIM homeobox protein 1; Homeobox protein Lim-1; hLim-1MolecularWeight(Da):
44808Observed Band(KD):
44Function:
domain:The LIM domains exert a negative regulatory function and disruption of the LIM domains produces an activated form. In addition, two activation domains and a negative regulatory domain exist C-terminally to the homeobox.,function:Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,subunit:Interacts with LDB1 via the tandem LIM domains.,tissue specificity:Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines.,Subcellular Location:
nucleus,protein complex,Expression:
Cerebellum,Fetal brain,Ovary,
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Catalog Number
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