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LBP Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72544

  • Amount:

    100ul

  • Applications:

    WB;ELISA;IHC-p

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human LBP. AA range:221-270

  • Source:

    Polyclonal, Rabbit

  • Immunohistochemical analysis of paraffin-embedded Human liver. 1, Antibody was diluted at 1:100(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

  • Gene Name:

    LBP

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Background:

    lipopolysaccharide binding protein(LBP) Homo sapiens The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012],

  • Protein Name:

    Lipopolysaccharide-binding protein

  • Human Gene Id:

    3929

  • Human Swiss Prot No:

    P18428

  • Mouse Gene Id:

    16803

  • Mouse Swiss Prot No:

    Q61805

  • Rat Swiss Prot No:

    Q63313

  • Specificity:

    LBP Polyclonal Antibody detects endogenous levels of LBP protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    LBP; Lipopolysaccharide-binding protein; LBP

  • MolecularWeight(Da):

    53384

  • Observed Band(KD):

    53

  • Function:

    function:Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.,similarity:Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.,

  • Subcellular Location:

    extracellular region,extracellular space,cell surface,membrane,extracellular exosome,

  • Expression:

    Liver,

  • Western Blot analysis of various cells using Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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Catalog Number

  • Amount:100ul
  • Price:225$

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LBP Polyclonal Antibody | EnoGene Biotech Co. Ltd