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LASS4 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72536

  • Amount:

    100ul

  • Molecular Weight:

    46399 DaObserved Band:46 KD

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse; Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using LASS4 Polyclonal Antibody

  • Gene Name:

    CERS4

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Ceramide synthase 4

  • Human Gene Id:

    79603

  • Human Swiss Prot No:

    Q9HA82

  • Mouse Swiss Prot No:

    Q9D6J1

  • Specificity:

    LASS4 Polyclonal Antibody detects endogenous levels of LASS4 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4

  • Background:

    function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,

  • Function:

    function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,

  • Subcellular Location:

    Endoplasmic reticulum membrane ; Multi-pass membrane protein .

  • Expression:

    Cerebellum,Embryo,Lung,

  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LASS4 Antibody. The picture on the right is blocked with the synthesized peptide.

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