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Cell Signal Transduction Research Antibodies
Laminin γ-3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight172051 Da
Protein NameLaminin subunit gamma-3
Human Gene Id10319
Human Swiss Prot NoQ9Y6N6
Mouse Gene Id23928
Mouse Swiss Prot NoQ9R0B6
SpecificityLaminin γ-3 Polyclonal Antibody detects endogenous levels of Laminin γ-3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameLAMC3; Laminin subunit gamma-3; Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma
Observed Band(KD)170
Functiondomain:Domain IV is globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type A domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 11 laminin EGF-like domains.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Gamma-3 is a subunit of laminin-12.,tissue specificity:Broadly expressed in: skin, heart, lung, and
Subcellular Locationextracellular region,proteinaceous extracellular matrix,basement membrane,membrane,
ExpressionPlacenta,Spleen,Testis,Whole embryo,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human LAMC3. AA range:1361-1410
Gene NameLAMC3
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundlaminin subunit gamma 3(LAMC3) Homo sapiens Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biol
Conjugated Antibody
This product is also available conjugated. Format: E20-72532-Conjugate. Price: $485 / Size: 100μl.
E20-72532-FITC$485 / 100μlE20-72532-Biotin$485 / 100μlE20-72532-HRP$485 / 100μlE20-72532-AP$485 / 100μlE20-72532-AF350$485 / 100μlE20-72532-AF405M$485 / 100μlE20-72532-AF488$485 / 100μlE20-72532-AF514$485 / 100μlE20-72532-AF532$485 / 100μlE20-72532-AF555$485 / 100μlE20-72532-AF568$485 / 100μlE20-72532-AF405S$485 / 100μlE20-72532-AF405L$485 / 100μlE20-72532-AF546$485 / 100μlE20-72532-AF594$485 / 100μlE20-72532-AF610$485 / 100μlE20-72532-AF635$485 / 100μlE20-72532-AF647$485 / 100μlE20-72532-AF680$485 / 100μlE20-72532-AF700$485 / 100μlE20-72532-AF750$485 / 100μlE20-72532-AF790$485 / 100μlE20-72532-APC$485 / 100μlE20-72532-PE$485 / 100μlE20-72532-Cy3$485 / 100μlE20-72532-Cy5$485 / 100μlE20-72532-Cy5.5$485 / 100μlE20-72532-Cy7$485 / 100μlE20-72532-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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