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KV3.1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-72510

  • Amount:

    100ul

  • Molecular Weight:

    57942 DaObserved Band:60 KD

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    Synthesized peptide derived from KV3.1 . at AA range: 190-270

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using KV3.1 Polyclonal Antibody

  • Gene Name:

    KCNC1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

  • Protein Name:

    Potassium voltage-gated channel subfamily C member 1

  • Human Gene Id:

    3746

  • Human Swiss Prot No:

    P48547

  • Mouse Gene Id:

    16502

  • Mouse Swiss Prot No:

    P15388

  • Rat Gene Id:

    25327

  • Rat Swiss Prot No:

    P25122

  • Specificity:

    KV3.1 Polyclonal Antibody detects endogenous levels of KV3.1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    KCNC1; Potassium voltage-gated channel subfamily C member 1; NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4

  • Background:

    This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both "b" and "alpha", while the shorter isoform has been called both "a" and "beta" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014],

  • Function:

    domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,domain:The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.,function:Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.,similarity:Belongs to the potassium channel family. C (Shaw) subfamily.,subunit:Heteromultimer with KCNG3, KCNG4 and KCNV2.,

  • Subcellular Location:

    Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Cell junction, synapse, presynaptic cell membrane . Localizes in parallel fiber membranes, distributed on the perisynaptic and extrasynaptic membranes away from the active zones. .

  • Expression:

    PCR rescued clones,

  • Western Blot analysis of K562 cells using KV3.1 Polyclonal Antibody

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Catalog Number

  • Amount:100ul
  • Price:225$

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KV3.1 Polyclonal Antibody | EnoGene Biotech Co. Ltd