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KKIALRE Polyclonal Antibody
Datasheet
Catalog Number:
E20-72481Amount:
100ulMolecular Weight:
41701DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CDKL1. AA range:281-330Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using KKIALRE Polyclonal Antibody diluted at 1:500
Gene Name:
CDKL1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Cyclin-dependent kinase-like 1Human Gene Id:
8814Human Swiss Prot No:
Q00532Mouse Swiss Prot No:
Q8CEQ0Rat Gene Id:
314198Rat Swiss Prot No:
Q66HE7Specificity:
KKIALRE Polyclonal Antibody detects endogenous levels of KKIALRE protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CDKL1; Cyclin-dependent kinase-like 1; Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALREObserved Band(KD):
42Background:
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],Function:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in kidney, and to a lower extent in ovary.,Subcellular Location:
Cytoplasm . Nucleus .Expression:
Highly expressed in kidney, and to a lower extent in ovary.
- Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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